Knightley is the face of an Amnesty International campaign to support human rights, marking the 60th anniversary of the United Nations Universal Declaration of Human Rights. In November 2010, Knightley became patron of the Spinal Muscular
Atrophy (SMA) Trust, a British charity that funds medical research into
the disease spinal muscular atrophy. Knightley contributed her voice to a 2007 Robbie the Reindeer animation, all profits of which will be donated to Comic Relief. In 2004, she travelled to Ethiopia on behalf of that charity.
In April 2009, Knightley appeared in a video to raise awareness of domestic abuse entitled Cut shot for Women's Aid.The video created controversy, with some sources calling it too graphic, while other groups support the video for showing a realistic depiction of domestic violence.She posed for photos for WaterAid in 2005 and also for the American
Library Association's "Read" campaign (a promotional poster of Pride & Prejudice).
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